CAS NO 497-30-3 L Ergothioneine Skin Care
|Place of Origin:||china,guangdong|
|Brand Name:||no brand|
Payment & Shipping Terms:
|Minimum Order Quantity:||1kg|
|Packaging Details:||1kg or 500g in a bottle, 9 bottle in a carton|
|CAS NO:||497-30-3||Product Name:||Ergothioneine|
|Application:||Cosmetic Raw Materials||Certification:||ISO|
|Shelf Life:||2 Years||Test Method:||HPLC UV|
|MOQ:||1kg||Storage:||Cool Dry Place|
|Production Method:||Microbial Fermentation||Product Content:||99.9% Mannitol And 0.1% Ergothioneine|
497 30 3 l ergothioneine skin care,
ISO l ergothioneine skin care,
497 30 3 L ergothioneine for skin
Anti - aging Super anti-oxidant ability CAS NO 497 - 30 - 3 L Ergothioneine EGT
Ergothioneine is a naturally occurring amino acid and is a thiourea derivative of histidine, containing a sulfur atom on the imidazole ring. This compound occurs in relatively few organisms, notably Actinobacteria, Cyanobacteria, and certain fungi. Ergothioneine was discovered in 1909 and named after the ergot fungus from which it was first purified, with its structure being determined in 1911.
In humans, ergothioneine is acquired exclusively through the diet and accumulates in erythrocytes, bone marrow, liver, kidney, seminal fluid, and eyes.In vitro, ergothioneine requires a specific transporter, ETT, also known as OCTN1 (gene symbol SLC22A4), to enter cells. Although the effect of ergothioneine in vivo is an active area of research, its physiological role in humans is undetermined. Ergothioneine is sold as a dietary supplement
Metabolism and sources
Ergothioneine has been found in bacteria, plants, and animals, sometimes at millimolar levels.Foods found to contain ergothioneine include liver, kidney, black beans, kidney bean, and oat bran, with the highest levels in bolete and oyster mushrooms. Levels can be variable, even within species and some tissues can contain much more than others. In the human body, the largest amounts of ergothioneine are found in erythrocytes, eye lens, semen,and skin.
Although many species contain ergothioneine, only a few make it; the others absorb it from their diet or, in the case of plants, from their environment.Biosynthesis has been detected in Actinobacteria, such as Mycobacterium smegmatis and certain fungi, such as Neurospora crassa.
The metabolic pathway to produce ergothioneine starts with the methylation of histidine to produce histidine betaine (hercynine). The sulfur atom is then incorporated from cysteine.The biosynthetic genes of ergothioneine have been described in Mycobacterium smegmatis, Neurospora crassa, and Schizosaccharomyces pombe.
Other species of bacteria, such as Bacillus subtilis, Escherichia coli, Proteus vulgaris, and Streptococcus, as well as fungi in the Saccharomycotina cannot make ergothioneine.
Ergothioneine is a thiourea derivative of the betaine of histidine and contains a sulfur atom bonded to the 2-position of the imidazole ring. Typical of thioureas, ergothioneine is less reactive than typical thiols such as glutathione towards alkylating agents like maleimides. It also resists oxidation by air. However, ergothioneine can be slowly oxidized over several days to the disulfide form in acidic solutions.
|Certificate of Analysis|
|Produce Name||Ergothioneine||Product batch number||20201009|
|Produce date||09th.10.2020||Shelf life||2 year|
|Inspection date||20th.10.2020||Date of report||23th.10.2020|
|Inspection standrd||Safety and Technical standards for Cosmetics 2015|
|Inspection items||Inspection standards||Test result|
|Character||White Powder||Meet the standard|
|Identification||The HPLC profile is consistent with the reference substance||Meet the standard|
|PH||5.0-8.0||Meet the standard|
|Solution Appearance||Colorless to light yellow transparent liquid||Meet the standard|
|Sulfate||compared with the control solution,no more concentrated||Meet the standard|
|Ammonium salt||compared with the control solution,no more concentrated||Meet the standard|
|Loss on drying||The Weight loss shall not be excessive (0.2%)||Meet the standard|
|Residue on ignition||not allowed (0.1%)||Meet the standard|
|Iron Salt||compared with the control solution,no deeper||Meet the standard|
|Heavy metal||Contain no more than 10 parts per million of heavy metals||Meet the standard|
|Arsenic||should meet the regulations (0.0001%)||Less than 0.0001%|
|Aerobic plate count (CFU/g)||Less than or equal to 100||Meet the standard|
|Total mold and yeast (CFU/g)||Less than or equal to 50||Meet the standard|
|Pseudomonas aeruginosa(cfu/g)||not detected||not detected|
|Staphyloococcus aureus (CFU/g)||not detected||not detected|
|Escherichia coli(CFU/g)||not detected||not detected|
|Candida albicans(CFU/g)||not detected||not detected|
|Salmonella (CFU/g)||not detected||not detected|
|Assay||Caculated as dry product,HPLC shall not be less than 98.0%||Meet the standard|
|Conclusion||This Product meets the testing standards
1.Accelerate fat oxidation reaction
2.Protect mitochondria from damage
3.Resist the damage of ozone to cells
4.Protect DNA from UV-A damage
5.Inhibit the expression of TNF-α and MMP-1 to prevent photoaging
6.Anti-aging, prevent various diseases
7.Cell freshness agent
1.Experience:3-year export experiences
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1kg/bag or according to your requirements.
25kgs/drum or according to your requirements.